Bacteria complete genomes

TECHNOLOGY SERVICES

Product introduction
Common problem
Classic case
Result display

Product introduction

The Smart Bacterial Completed Map refers to first assembling the genome with high-accuracy second-generation data (Illumina or BGI-seq), during the assembly process, Nanopore long sequences are used to cover the branched points and connect them into a completed map. Finally, the second-generation data is used for error correction. This strategy can quickly obtain high-quality bacterial genome complete maps, and the error rate is reduced to the 0.001% level.

Advantages of Smart Bacteria Completed Map

Faster: complete analysis within one week after sequencing.
More economical: Get more result with less cost.
More accurate: The second-generation data determines the accuracy, and the error rate is as low as 0.001%.
No preference: no GC preference, evenly coverage of the whole genome, high GC/low GC genome preferred.

Application direction

Pathogenic microorganisms: human infection, animal infection, plant infection, etc.
Industrial direction: antibiotic production, yogurt fermentation, energy utilization, etc.
Environmental science: microbial resource utilization, heavy metal treatment, foreign defense control, extreme environmental microorganisms and other

Paper recommend

Nicola DM, Liam PS, et al. Comparison of long-read sequencing technologies in the hybrid assembly of complex bacterial genomes [J]. Microbial Genomics, 2019.
Michelle T S , Settlage R E , Lahmers K K , et al. Fusobacterium Genomics Using MinION and Illumina Sequencing Enables Genome Completion and Correction[J]. Msphere, 2018, 3(4).
Margaret M C L , Wyres K L , Duchêne Sebastian, et al. Population genomics of hypervirulent Klebsiella pneumoniae clonal group 23 reveals early emergence and rapid global dissemination[J]. Nature Communications, 2018.